Bleach is the a DNA researcher's best friend-it destroys DNA and can be liberally applied to all lab surfaces, removing a potential source of contamination (Dissing et al. 2008;Gilbert et al.... read more ›
Since DNA is stable to alkaline hydrolysis, alkaline based cleaners and detergents may not be effective, or efficient. We recommend testing 1-2% Citranox® Liquid Acid Cleaner and Detergent, pH 2.5 for removing DNA. Acids at high temperatures are capable of breaking the DNA molecule into its components.... see more ›
Chlorine is a strong antimicrobial substance which due to its oxidising capacity can kill bacteria by destroying their cell-wall by altering it physically, chemically, biochemically and inhibiting DNA synthesis, and ultimately terminating the cell's vital functions (Virto et al., 2005; Gray et al., 2013).... see details ›
In summer, the time period for erasing the bulk of DNA was 4 hours regarding epithelial samples and more than 1 day for blood samples in pond and river environments. All in all, the results demonstrate that DNA could still be recovered from clothes exposed to water for more than 1 week.... read more ›
Because hydrogen peroxide actually forms as a product of metabolism and can do some nasty things. It can break apart to yield hydroxyl radicals that attack important biochemicals like proteins and DNA.... see more ›
Researchers at the University of Valencia tested oxygen bleach on blood-stained clothing for two hours and found that it destroys all DNA evidence.... read more ›
There are a number of reasons why bleach isn't a good fit for cleaning biohazards found in crime scenes. A scientist from the University of Michigan found out that bleach is a very reactive chemical and any contact with cellular components will cause an adverse reaction once it hits the cells.... see details ›
- Phenol-Chloroform Extraction. Phenol chloroform extraction, normally followed by ethanol precipitation, is the traditional method to remove protein from a DNA sample. ...
- Ethanol Precipitation. ...
- Silica Column-Based Kits. ...
- Anion Exchange. ...
- Magnetic Beads. ...
- 16 Comments.
Environmental factors, such as heat and humidity, can also accelerate the degradation of DNA. For example, wet or moist evidence that is packaged in plastic will provide a growth environment for bacteria that can destroy DNA evidence.... view details ›
What's the shelf life of DNA? About a month to a million years, theoretically. The decay rate of DNA depends on the conditions of its storage and packaging. Above all, it depends on whether the DNA is exposed to heat, water, sunlight, and oxygen.... view details ›
Knox and Sollecito were on the right track: Bleach contains sodium hypochlorite, an extremely corrosive chemical that can break the hydrogen bonds between DNA base pairs and thus degrade or “denature” a DNA sample.... see more ›
Swabs do not require refrigeration. In fact, after samples are collected, they are good for up to six months as long as the swabs are kept in a cool, dry place. It is easier and faster for a lab to extract DNA from a cheek swab than from blood.... view details ›
Conventional methods to destroy DNA include irradiating with ultraviolet light, using enzymes such as DNAse I 8 , applying high temperature of over 200°C 9,10 , or using bleach 11 .... see more ›
“Our work definitively shows that external factors, like drinking alcohol, can damage DNA in blood stem cells, meaning it could also damage DNA in other types of stem cells,” says Patel.... read more ›
Knox and Sollecito were on the right track: Bleach contains sodium hypochlorite, an extremely corrosive chemical that can break the hydrogen bonds between DNA base pairs and thus degrade or “denature” a DNA sample.... see details ›
Household bleach (sodium hypochlorite) is effective for removal of DNA from surfaces . Use freshly prepared solution of household bleach (1 % sodium hypochlorite)  for 30 minutes of contact time on the surface followed by rinsing with ethanol or water.... continue reading ›